List of Experiment for Pharmacology (Listed by Ex Pharm Software)

Experimental Pharmacology Experiments

1-5. Experiment on the Effects of Various Drugs (Mydriatic, Miotic, and Local Anaesthetic) on Rabbit's Eye

1. Epinephrine
2. Atropine
3. Ephedrine
4. Physostigmine
5. Lignocaine

6-8. Study of Analgesic Activity

6. Using "Tail Flick Apparatus" (Analgesiometer)
7. Using "Hot Plate Apparatus" (Analgesiometer)
8. By "Writhing Test"

9-11. Study of Specific Drug Activities

9. Antihistaminic/Anti-allergic drugs by mast cell stabilization method (using "Histamine Chamber")
10. Muscle Relaxant activity using "Rota-Rod Apparatus"
11. CNS Depressants & Stimulants using "Actophotometer"

12-14. Study of Drugs Acting on CNS (Including Anxiolytic Activity)

12. Elevated Plus Maze Method
13. Pole Climbing Method
14. Evaluation of Anti-Psychotic and Sedative Drugs

15-18. Study of Anticonvulsant and Neurological Activities

15. Anticonvulsant activity using "Electro Convulsiometer"
16. PTZ-induced convulsions in mice
17. Effect of hepatic microsomal enzyme inducers on phenobarbitone sleeping time in mice
18. Action of strychnine/anaesthetic on frog neurons (excitability) 

     

19-22. Various Physiological Studies

19. Test for pyrogens using rabbits
20. Effect of drugs on isolated guinea pig ileum (in-vitro)
21. Study of respiratory depression effect on rabbits
22. Study of stereotype and anti-catatonic activity of drugs on mice

23-24. Experiments on Thyroid and Blood Sugar Regulation

23. Effect of thyroxin, TSH, and propylthiouracil on metabolism
24. Effect of insulin (hypoglycemic activity) and alloxan on blood glucose

25-27. Study of Anti-Inflammatory and Diuretic Activities

25. Anti-inflammatory activity using carrageenan-induced paw edema method
26. Study of diuretic activity using metabolic cage

28-31. Experiments on Amphibian Nerve-Muscle (Sciatic Nerve and Gastrocnemius Muscle) Preparation

28. Recording of Simple Muscle Twitch
29. Effect of Temperature
30. Effect of Stimuli of Increasing Frequency
31. Effect of Stimuli of Increasing Strength

32-39. Experiment on Effect of Various Drugs on Isolated Frog's Heart (Dose Response Curve - DRC)

32. Epinephrine
33. Norepinephrine
34. Isoprenaline
35. Calcium chloride
36. Propranolol
37. Acetylcholine
38. Potassium chloride
39. Atropine sulphate

40-53. Experiments on Effect of Different Drugs on Dog Blood Pressure & Heart Rate

• Virtual Practice: Effects of drugs on dog BP and heart rate

40. Epinephrine (Adrenaline)
41. Norepinephrine (Noradrenaline)
42. Isoprenaline
43. Acetylcholine
44. Histamine
45. Ephedrine
46. Phentolamine
47. Propranolol
48. Atropine
49. Cimetidine
50. Carotid Occlusion
51. Central Vagus
52. Peripheral Vagus

• Effects of Vasopressor and Vasodepressor with Appropriate Blockers
• Virtual Practice: Reversal action of adrenaline on blood pressure and heart rate
• Virtual Practice: Reversal action of acetylcholine on blood pressure and heart rate

54-55. Experiments on "Langendorff’s Apparatus"

• Effect of coronary vasodilators on isolated heart
• Effect of parasympathomimetics

56-66. Bioassay and Dose-Response Curve (DRC) Experiments

56. DRC, effect of agonist and antagonist, and bioassay of histamine using guinea pig ileum (matching method)
    57-58. Bioassay of acetylcholine using guinea pig ileum
    59-60. Bioassay of oxytocin using rat uterine horn
    61-62. Bioassay of serotonin using rat fundus strip
    63-64. Bioassay of acetylcholine using rat ileum
    65-66. DRC and determination of pD2 value for acetylcholine on frog rectus abdominis muscle

67-72. Pharmacological Analysis of Histamine and Serotonin

67-68. DRC and determination of pD2 value of histamine on guinea pig ileum
69-70. DRC and determination of pD2 value of serotonin on rat stomach (fundus strip)
71-72. DRC and determination of pA2 value of prazosin using rat anococcygeus muscle (Schild's plot method)

73-76. Study of Specific Drug Effects

73. Study of anti-ulcer activity using pylorus ligation method
74. Effect of acetylcholine (spasmogens) using rabbit jejunum
75. Effect of different drugs on ciliary motility
76. Effect of saline purgatives on frog intestine

77-78. Determination of Acute Irritation of a Test Substance

77. Skin irritation (including edema formation)
78. Eye irritation

79-86. Additional Interactive Modules in Experimental Pharmacology

79. Animals used in experimental pharmacology
80. Instruments used in experimental pharmacology
81. Physiological salt solutions used in experimental pharmacology
82. Different routes of drug administration
83. Blood withdrawal techniques
84. Methods of anesthesia & euthanasia
85. Dose calculation in pharmacological experiments
86. Calculation of pharmacokinetic parameters

Biostatistics Methods in Experimental Pharmacology

                                                       

                                                                 END OF THE DOCUMENT

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 1. Chapters In Pharmacology

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