Pharmacy-Pharmacology - Sample Multiple Choice Questions (MCQs)

Select the Alphabet of the best answer for following Questions :

1. The action of histamine that is not mediated through III receptors is:

a) Release of EDRF from vascular endothelium resulting in vasodilatation
b) Direct action on vascular smooth muscle causing vasodilatation
c) Bronchoconstriction
d) Release of catecholamines from adrenal medulla

2. Histamine exerts the following actions except:

a) Dilatation of large blood vessels
b) Dilatation of small blood vessels
c) Stimulation of isolated guinea pig heart
d) Itching

3. Fall in blood pressure caused by larger doses of histamine is blocked by:

a). H1 antihistaminic alone
b). H2 antagonists alone
c) Combination of H1 and H2 antagonists
d). None of the above

4. The drug that can directly release histamine from mast cells without involving antigen
antibody reaction is:

a) Aspirin
b) Procaine
c) Morphine
d) Sulfadiazine

5. Which one is not medicine distribution system for inpatient?
a) Floor stock system
b) Patient prescription system
c) FEFO system
d) Unit dose system

6. Who is responsible for preparation of hospital formulary?

a) Director
b) DTC
c) Health ministry
d). Department of head

7. Normal serum level of sodium lies between

a). 2.5-4.0 mmol/l

b). 3.5-5.0 mmol/l

c) 4.5-6.0 mmol/l

d). 5.5-7.0 mmol/l

8. To compare the safety of one medicine with another medicine it would be necessary to:

a). Review the evidence from Phase 1 clinical trials.

b). Review the evidence from Phase II clinical trials.

c) Review the evidence from a post marking clinical trial.

d). Review the number of reports obtained from the yellow card adverse drug reaction reporting scheme

9. A 58-year-old African man presents with pitting oedema of his ankles. He suffers from recently diagnosed hypertension, but is otherwise healthy. Blood results show low albumin and a urine dipstick is positive for protein. The most appropriate initial treatment is:

a). High protein diet

b). Diuretics

c) Prophylactic anticoagulation

d) ACE inhibitor

10. Parkinson's disease (PD) is characterized by a nigrostriatal deficiency of:

a). Acetylcholine

b). Dopamine

c) Norepinephrine

d). Serotonin

11. d-Penicillamine enhance toxicity of

a) Abciximab
b) Phenindione
c) Digoxin
d) Acenocoumarol

12. Which is also known as “Good Cholesterol”?
a) VLDL
b) LDL
c) HDL
d) Triglycerides

13. EACA is used as
a) Thrombolytics agents
b) Anticoagulant
c) Antiplatelet drugs
d) Antifibrinolytics

14. Cetirizine drug belongs to which following category?
a) Migraine
b) Antihistaminics
c) Histaminergic Agonists
d) 5-HT Antagonist

15. Budesonide belongs to which following category?
a) Anticholinergic
b) Mast Cell Stabilizers
c) Systemic Corticosteroids
d) Inhaled Corticosteroids

16. Which of the following is a prodrug?

a). Enalapril

b). Metformin

c) Ibuprofen

d). Paracetamol

17. All of the followings are regulated by Drug Act (2035 BS) except.....

a). Patent right

b). Clinical trials

c). Drug advertisement

d). Price control

18. is the study of dosage form design, including associated manufacturing technique.

a). Pharmaceutics

b) Pharmacology

c). Pharmacognosy

d). Pharmacokinetics

19. The international pharmacopoeia was produced by

a). The international union of pharmacists

b). International pharmaceutical federation (FIP)

c). European Union (EU)

d). World Health Organization (WHO)

20. Which of the following drug is known microsomal enzyme inducer?

a) Rifampicin
b) Isoniazid
c) Pyrazinamide
d) Ethambutol

21. A newly married lady aged 27 years was relying on Oral Contraceptive pills for postponing the pregnancy for few months. In the meantime, she suffers from pulmonary tuberculosis and the physician put her on ATT (Anti-tubercular therapy). She conceived despite the regular intake of OCP. Which of the following drug is responsible for it?

a). Rifampicin

b). Isoniazid

c) Pyrazinamide

d). Ethambutol

22. A newly married lady aged 27 years was under Oral Contraceptive pills for postponing the pregnancy for few months. In the meantime, she suffers from pulmonary tuberculosis and the physician put her on ATT (Anti-tubercular therapy). She conceived despite the regular intake of OCP. Which of the following would have been the right choice?

a). Take ATT in the morning and the OCP at night

b). Take 2nd line anti-tubercular drugs while she is on OCP

c) Adopt surgical method of contraception and continue ATT

d) Use non-hormonal means of temporary contraception while she is on ATT

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