1.0 SCOPE
This standard testing procedure is suitable for the determination of water-soluble extractive value in Choorna/Kvatha Choorna.
2.0 PURPOSE
The purpose of the document is to establish a method for water-soluble extractive value in Choorna/Kvatha Choorna.
3.0 RESPONSIBILITY
The expert and trained chemist are responsible for following this procedure. The technical manager is responsible for implementing this procedure.
4.0 REQUIREMENTS
4.1 Apparatus
4.1.1 Analytical balance
4.1.2 Shaker
4.1.3 Water bath
4.1.4 Hot Air Oven
4.2 Glassware
4.2.1 conical stoppered Flask
4.2.2 Petri-dish
4.2.3 Funnel
4.2.4 Measuring cylinder
4.3 Reagent
4.3.1 Water & chloroform to make chloroform water.
(2.5 ml chloroform in purified water to produce 1000 ml).
5.0 PROCEDURE
5.1 Weigh 2.0g to 5.0 g of sample in the stoppered volumetric flask.
5.2 Add 100 ml of Chloroform water to it.
5.3 Shake it for 06 hours continuously on the shaker.
5.4 Keep it still for 18 hours.
5.5 Filter it with Whatman filter paper (No.-1) in a previously dried dish.
5.6 Take 25 ml of solvent into a previously dried and weighed petri dish at 105°C for 30 min.
5.7 Now evaporate the solvent by keeping the Petri dish in the water bath.
5.8 Keep the petri-dish in the oven for drying at 105°C for 1 hr.
5.9 Remove the dish from the oven and place it in the desiccator for cooling.
5.10 Note down the dry weight of the petri-dish.
6.0 CALCULATION
[ (W3-W2 )/ W1 ] X100 X 100/25
Where,
W1=Weight of dish+
sample weight, in g
W2=Weight of the empty dish, in g
W3 =Weight of dish+Extractive residue, in g
7.0 ATTACHMENTS
Appendix-1: Flow chart for solvent soluble extractive value in Choorna/Kvatha Choorna.
8.0 REFERENCES
A.P.I. Part I, Vol-VIII; First Edition-2011.
Hi. I’m Writer of Researchsop.com. ’ ’ Please share these SOPs to all concern pharma people for their development. I like to fullfill the need of curious people. These things inspire me to make things looks better.
0 comments:
Post a Comment