2.0 RESPONSIBILITY: It is the responsibility of the Animal Facility Personnel, In-charge of the animal house facility, the Animal facility supervisor, and all Veterinary care staff.
3.0 PROCEDURE: An effective pest control program should be able to prevent access, deny harborage and eradicate any pests present.
3.1 If the animal is no longer under experimentation and is suffering or is likely to suffer adverse effects, the person in-charge should get them killed/sacrificed immediately.
3.2 It should be a practice to immediately remove the killed/sacrificed animals so that the other animals are not frightened or antagonized.
3.3 Insect sticky traps and live mousetraps should be used in all animal rooms and support areas for vermin monitoring and control.
3.4 Devices should be placed on the floor along the walls or corners.
3.5 Devices should be placed in such a way that they do not hinder the movement, but should also be within the reach of Animal Care Facility (ACF) personnel at the time of inspections.
3.6 Live traps should be baited using standard rodent feed and should be positioned in a way that their entry faces the wall.
3.7 Traps should be returned to their original location after inspection.
3.8 Minor caulking and sealing of cracks and crevices, deemed to be entry points, should be done for preventing entry to the interior of the facility.
3.9 Daily inspection and record maintenance should be done to show the presence or evidence of vermin in the facility’s pest management logbook.
3.10 Date, location, and type of pest infestation should be kept in record.
3.11 If the rodent is feral, blood should be sent for testing.
3.12 All diagnostic testing submitted would be directed by a Veterinarian.
3.13 If the rodent is severely moribund, the rodent should be sacrificed using professional judgment and blood should be collected for testing if necessary.
3.14 All the gaps are sealed and fitted around in walls or floors.
3.15 Outside doors should be kept closed all the time.
3.16 All the materials should be stored at least one foot away from the wall.
3.17 All the materials are kept on the pallets and the containers of the products should be covered properly.
3.18 Both outside and inside of the premises should be inspected frequently (e.g. weekly) for any signs of pests.
3.19 Physical barrier means should be used (e.g. rodent traps) and whenever there are signs of rodents seen; Rotarod apparatus should be fixed outside the unit.
3.20 An insect sprayer should be used to kill the flying insects and should be cleaned on the daily basis.
3.21 Format for pest control monitoring record sheet should be provided.
4.0 PRECAUTIONS:
4.1 There should be no cracks or breaks or leakages in the Animals House facility.
4.2 Rodents or pests should be immediately tracked and removed.
4.3 The pest control should be done in a way that the experimental animals are not harmed in any way.
4.4 Animal facilities should be supervised and quality audits should be done from time to time.
5.0 REFERENCES:
5.1 Bernal J, Baldwin M, Gleason T, Kuhlman S, Moore G, Talcott M. Guidelines for rodent survival surgery. J Invest Surg. 2009;22:445–451. [PubMed]
5.2 Besselsen DG, Franklin CL, Livingston RS, Riley LK. Lurking in the shadows: Emerging rodent infectious diseases. ILAR J. 2008;49:277–290. [PMC free article] [PubMed]
5.3 Bradfield JF, Schachtman TR, McLaughlin RM, Steffen EK. Behavioral and physiological effects of inapparent wound infection in rats. Lab Anim Sci. 1992;42:572–578. [PubMed]
5.4 Brown MJ. Aseptic surgery for rodents. Rodents and Rabbits: Current Research Issues. Niemi SM, Venable JS, Guttman HN, editors. Bethesda, MD: Scientists Center for Animal Welfare; 1994. pp. 67–72.
5.5 Brown MJ, Schofield JC. Perioperative care. Essentials for Animal Research: A Primer for Research Personnel. Bennett BT, Brown MJ, Schofield JC, editors. Washington: National Agricultural Library; 1994. pp. 79–88.
END OF THE DOCUMENT
You may like to read these links:
1. List of In-vivo laboratory Vendors (Capex)
2. List of SOPs and Documents for CPCSEA
3. List of All SOPs and Documents for Laboratory Instruments and Equipment
4. List of All SOPs and Documents for the Animal House Facility
5. List of All SOPs and Documents for the In-vivo Laboratory
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