1.0 OBJECTIVE: To design a Standard Operating Procedure for Feeding and Bedding Laboratory animals.
2.0 RESPONSIBILITY: It is the responsibility of the Animal Facility Personnel and In-charge of the animal house facility.
3.0 FACILITIES:
3.1 The
bedding materials are efficient and hygiene operation of animal facilities.
Durable moisture-proof, fire resistant, seamless materials are most desirable
for interior surfaces including vermin and pest resistance.
3.2 Corridors
are enough to facilitate the movement of personnel as well as equipment and
should be kept clean.
3.3 Utilities
such as water lines drain pipes and electrical connections should be accessible
through service panels or shafts in corridors outside the animal rooms.
4.0 PROCEDURE:
4.1 The
feed and water of the laboratory animals was checked daily.
4.2 The
feed was changed as soon as there was any requirement
4.3 Feed
with proper nutritional values was served to the laboratory animals.
4.4 The
bedding was changed in every two days.
4.5 The
dirty and filthy bedding was removed.
4.6 The
trays were cleaned, dried and then fresh bedding was filled.
4.7 The
temperature was maintained as per the requirement and the weather.
5.0 PRECAUTIONS:
5.1 The
feed and water requirement of the laboratory animals should be checked daily.
5.2 The
animals should not be given anything else to eat than the prescribed feed.
5.3 The
nutritional chart of the animals should be checked and the feed should be
purchased from an authorized vendor.
5.4 Water bottled should be thoroughly washed and
fresh water should be given to the laboratory animals.
6.0 REFERENCES:
6.1 Haines DC, Gorelick PL, Battles JK, Pike KM, Anderson RJ, Fox JG, Taylor
NS, Shen Z, Dewhirst FE, Anver MR, Ward JM. Inflammatory large bowel disease in
immunodeficient rats naturally and experimentally infected with Helicobacter
bilis. Vet Pathol. 1998;35:202–208. [PubMed]
6.2 Hancock RB, Lanz OI, Waldron DR, Duncan RB, Broadstone RV, Hendrix PK.
Comparison of postoperative pain after ovariohysterectomy by harmonic
scalpel-assisted laparoscopy compared with median celiotomy and ligation in
dogs. Vet Surg. 2005;34:273–282. [PubMed]
6.3 Haskins SC, Eisele PH. Postoperative support and intensive
care. Anesthesia and Analgesia in Laboratory Animals. Kohn DF, Wixson
SK, White WJ, Benson GJ, editors. New York: Academic Press; 1997. pp. 381–382.
6.4 Hawkins P. Recognizing and assessing pain, suffering and distress in
laboratory animals: A survey of current practice in the UK with
recommendations. Lab Anim. 2002;36:378–395. [PubMed]
6.5 Hawkins P, Playle L, Golledge H, Leach M, Banzett R, Coenen A, Cooper J,
Danneman P, Flecknell P, Kirkden R, Niel L, Raj M. Newcastle Consensus
Report on Carbon Dioxide Euthanasia of Laboratory Animals. 2006. [accessed
April 10, 2010]. Available at www.nc3rs.org.uk/downloaddoc.asp?id=416andpage=292andskin=0.
6.6 Chamberlain GV, Houang E. Trial of the use of masks in
gynecological operating theatre. Ann R Coll Surg Engl. 1984;66:432–433. [PMC free article] [PubMed]
6.7 Coderre TJ, Katz J, Vaccarino AL, Melzack R. Contribution of central neuroplasticity to pathological pain: Review of clinical and experimental evidence. Pain. 1993;52:259–285. [PubMed]
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