2.0 RESPONSIBILITY: It is the responsibility of animal care personnel, Principal Investigator (PI), Animal House in-charge and Veterinary care personnel.
3.0 MATERIALS:
3.1 Illness/injury report
3.2 Veterinary care cage card, back
3.3 Case number labels
3.4 Treatment log
3.5 Green round stickers
4.0 PROCEDURES:
4.1 Observation of animals:
All animals were observed daily (including weekends and holidays) by animal care or veterinary care staff for illness, injury and general condition.
4.2 Submitting an illness/injury report:
4.2.1 Animal care staff that finds a sick or injured animal must complete the top (shaded) part of an illness/report.
4.2.2 A blank veterinary care card was placed on the cage of the affected animals.
4.2.3 The completed report was submitted to the veterinary care staff.
4.3 Opening a clinical case:
4.3.1 Veterinary care staff was assigned a unique case number. A label with the case number is placed on the veterinary care card and the number was recorded on the top right hand corner of the illness/injury report.
4.3.2 Veterinary care staff examined the animal and decided the best course of action for treatment in consultation with the PI.
4.3.3 For rodents, a carbon copy of the open case was placed in the blinder in each housing room.
4.4 Treatments:
4.4.1 Any treatment prescribed was clearly written on the illness/injury report and on the back of the veterinary care card or on a separate treatment record.
4.4.2 Each day, as the treatments were performed, the person performing them recorded the date, time if applicable, and their initials.
4.4.3 Minor treatments on rodents were performed by animal care staff.
4.4.4 Only trained animal care staff was allowed treat animals.
4.4.5 The treatment and re-check date was recorded in a treatment log created for each housing room.
4.4.6 A green round card sticker was placed on the veterinary care card to visually identify cages to be treated by animal care staff.
4.4.7 Animal care staff had performed treatment on the re-check date so that the veterinary care staff could evaluate the condition of the animals and modify treatments as needed. Modifications to treatments were clearly recorded on the treatment Log and on the veterinary care card.
4.4.8 When stopping a treatment or closing a case performed by animal care staff, the treatment was crossed off the treatment Log and the date and initials of the person closing the case were recorded in the appropriate columns. The green sticker was removed from the veterinary care card.
4.5 Contacting the PI or designate:
4.5.1 The contact information can be found on the cage card of the affected animal or in the master contact list. Alternatively, emergency contact information can be found in the Animal use protocols.
4.5.2 The date and initials of the person who contacted the PI or designate were recorded on the illness/injury report in the designated area.
4.5.3 Any additional information thus obtained was written on the illness/injury report.
4.6 Follow-up:
4.6.1 A re-check date was determined to follow-up on the condition of the animals. Most cases re-evaluated on a weekly basis but more critical cases can be seen more often and those cases which do not require close monitoring can be rechecked every two to four weeks.
4.6.2 Treatment can then be modified, stopped or the case closed.
4.7 Morbidity record:
New cases were recorded in the morbidity record. All information was filled, except for the “outcome” column.
5.0 PRECAUTIONS:
5.1 Any injury or illness observed in the animal should be immediately reported.
5.2 Proper labeling of the cages should be done.
5.3 Everything related to the animals should be reported to the PI.
6.0 REFERENCES:
6.1 Karas AZ. Postoperative analgesia in the laboratory mouse, Mus musculus. Lab Anim (NY) 2002;31:49–52.[PubMed]
6.2 Karas A, Danneman P, Cadillac J. Strategies for assessing and minimizing pain. Anesthesia and Analgesia in Laboratory Animals. Fish R, Brown M, Danneman P, Karas A, editors. San Diego: Academic Press; 2008. pp. 195–218.
6.3 Kirkden RD, Niel L, Stewart SA, Weary DM. Gas killing of rats: The effect of supplemental oxygen on aversion to carbon dioxide. Anim Welf. 2008;17:79–87.
6.4 Klaunberg BA, O’Malley J, Clark T, Davis JA. Euthanasia of mouse fetuses and neonates. Contemp Top Lab Anim Sci. 2004;43:29–34. [PubMed]
6.5 Klein L. Neuromuscular blocking agents. Principles and Practice of Veterinary Anesthesia. Short CE, editor. Baltimore: Williams and Wilkins; 1987. pp. 134–153.
END OF DOCUMENTS
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